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<p>Sections examined revealed an invasive carcinoma formed of crowded irregular tubular glandular formations lined by several layers of columnar malignant cells exhibiting moderate anaplasia and mitosis. The appendiceal mucosa is replaced by villous tumor with slender villi covered by tall columnar epithelial cells exhibiting moderate dysplasia. The tumor cells are extensively submucosa sparing the thinned out muscularis propria. The picture of adenocarcinoma arising on top of villous adenomatous polyp, Stage T1.</p><p><strong>- Histologic Type:</strong> Adenocarcinoma.</p><p><strong>- Histologic Grade:</strong> Moderately differentiated (Grade 2).<strong>Tumor Size:</strong> 1.5 cm in greatest dimension.</p><p><strong>-Anatomical Extent of Tumor:</strong> Tumor invades the submucosa but does not extend into the muscularis propria (<strong>pT1</strong>).</p><p><strong>-Lymphovascular Invasion:</strong> Not identified.</p><p><strong>-Perineural Invasion:</strong> Not identified.</p><p><strong>-Regional Lymph Nodes:</strong> None submitted for evaluation (<strong>Nx</strong>).</p><p><strong>-Pathologic Stage (AJCC):</strong> pT1,Nx, Mx.</p>
<p>Referred paraffin blocks and slides of appendicectomy specimen.</p>
<p class="ql-align-justify">Five referred paraffin blocks and five Hx&E stained slides were received.</p>
<h3><strong><em><u>Appendicectomy, Referred paraffin block and slides for review: </u></em></strong></h3><ul><li><strong>Adenocarcinoma, grade 2 arising on top of villous adenomatous polyp. Stage T1.</strong></li></ul><p><strong><u>COMMENT:</u></strong></p><p><strong>For assessment of margins of excision, please refer to original pathology report. </strong></p>
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