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<p class="ql-align-justify">Sections from both sites show an ulcerating mucosa with related diffuse and interglandular infiltration by intermediate sized to large undifferentiated cells. There is superimposed inflammatory cell infiltrate with focal necrosis. Possibilities include large cell non-Hodgkin's lymphoma and undifferentiated carcinoma. Marker study (CK, LCA, CD20, chromogranin, synaptophysin and Ki-67) is advised to reach a definitive diagnosis.</p>
<p class="ql-align-justify">Large antral ulcer on upper endoscopy and a cecal ulcer on colonoscopy.</p>
<h3 class="ql-align-justify">Two biopsies were received :</h3><ul><li class="ql-align-justify"><strong>A) Gastric: </strong>soft tissue fragments collectively measured 1 cm, totally embedded.</li><li class="ql-align-justify"><strong>B) Cecum:</strong> two soft tissue fragment collectively measured 0.4 cm, totally embedded.</li></ul>
<p><strong><em><u>Stomach and Cecum, endoscopic biopsies:</u></em></strong></p><ul><li><strong>Malignant undifferentiated large round cell tumor. </strong></li><li><strong>Recommended for typing by marker study.</strong></li></ul>
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