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<p class="ql-align-justify">Ulcerated gastric mucosal fragments infiltrated by an invasive moderately differentiated adenocarcinoma. The tumor is composed of crowded, irregular, and angulated and cribriform glands exhibiting fused and back-to-back architecture with minimal intervening stroma. These neoplastic structures are set within a desmoplastic background and are lined by atypical epithelial cells demonstrating nuclear enlargement, hyperchromasia, pleomorphism, loss of polarity, and prominent nucleoli.</p>
<p class="ql-align-justify">Upper endoscopy reveals a large, recently bleeding ulcerative lesion on the incisura angularis that extends to the antrum and upper gastric body, covered with white exudates, fresh blood, and black clots.</p>
<p class="ql-align-justify">Soft tissue fragments collectively measured 1.2 cm, totally embedded in one cassette.</p>
<p><strong><em><u>Gastric ulcer, endoscopic biopsy:</u></em></strong></p><ul><li><strong>Tubular adenocarcinoma, grade 2.</strong></li></ul>
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