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<p class="ql-align-justify">Sections examined show thyroid tissue composed of variably sized follicles, many of which are markedly dilated and irregular, consistent with nodular (multinodular) goiter. The follicles are lined by flattened to low cuboidal follicular epithelium without cytologic atypia. The follicular lumina contain abundant dense eosinophilic colloid, showing focal cracking and retraction artefact. There are extensive areas of dystrophic calcifications. Foci of stromal hyalinization, fibrosis, and cholesterol clefts are present. Occasional hemosiderin-laden macrophages are noted, suggestive of prior hemorrhage. No evidence of specific granulomas. No evidence of malignancy.</p>
<p><span style="color: rgb(45, 57, 65);">History of chronic obstructive pulmonary disease, presented with small hard mass noted at the 3rd trachea.</span></p>
<p>Hard tissue fragment measuring about 3.1 x 1 x 1 cm, totally embedded.</p>
<p><strong><em><u>Tracheal mass Excision biopsy:</u></em></strong></p><ul><li><strong>Calcified thyroid nodule in a background of multinodular goiter.</strong></li><li><strong>Negative for malignancy. </strong></li></ul>
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