TUMOR SUMMARY (CASE LEVEL):
• Procedure: Systematic biopsy.
• Positive specimen(s) or zone(s): Right apex, Right middle, Left apex, and Left middle.
• Histologic type: Prostatic adenocarcinoma, acinar type.
• Histologic grade: Total Gleason score = 9.
- Primary pattern: 5.
- Secondary pattern: 4.
- Grade group: 5/5.
• Intraductal carcinoma (IDC): Present.
• Cribriform glands: Not applicable.
• Tumor quantitation:
- Total number of cores: 6. - Number of positive cores: 4/6.
- Greatest percentage of core involvement by cancer in any core: 12%.
• Perineural invasion: Present.
• Lymphovascular invasion: Not seen.
• Periprostatic fat invasion: Not seen.
• Seminal vesicle invasion: Not seen.
Lower urinary tract symptoms and urinary retention, characterized by a moderately enlarged and mildly hard prostate on digital rectal examination, an elevated Total Prostate Specific Antigen of 222 ng/ml, free PSA 15.3 ng/ml, and ultrasound findings of a 60 g enlarged prostate.
Received in 6 containers, 1 from right apex, 2 right middle, 3 right base, 4 left apex, 5 left middle and #6 left base; tissue cores ranged from 1 to 1.2 cm long, submitted entirely.
PROSTATE; RT & LT apex, RT & LT middle, and RT & LT base; CORE BIOPSIES: