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<p><strong>SPECIMEN</strong></p><p>Specimen Laterality: Left</p><p>Specimen Procedure: Excision.</p><p><strong>TUMOR</strong></p><p>Histologic Type: Invasive carcinoma of no special type (NST)</p><p>Histologic Grade (Nottingham Histologic Score): Grade 2</p><p>Tumor Size (Greatest Dimension): 2.8 cm.</p><p>Ductal Carcinoma In Situ (DCIS): Not identified</p><p>Tumor-Infiltrating Lymphocytes (TILs): Intermediate</p><p>Extension to skin: Present with pagetoid spread to epidermis.</p><p>Lymphovascular Invasion (LVI): Present</p><p>Perineural Invasion (PNI): Present</p><p><strong>MARGINS</strong></p><p>Margin Status: Positive for invasive carcinoma</p><ul><li>Lateral Margin: Positive for invasive carcinoma</li><li>Deep Margin: Uninvolved by invasive carcinoma, but close (distance: 1 mm)</li></ul><p><strong>PATHOLOGIC STAGE </strong>CLASSIFICATION (AJCC 8th Edition)</p><p>Primary Tumor (pT): pT2.</p><p>Regional Lymph Nodes (pN): pNX (regional lymph nodes cannot be assessed)</p><p>Metastasis: pMx</p><p><br></p><p><br></p><p><br></p><p><br></p><p><br></p><p><br></p>
<p class="ql-align-justify">Lt. breast mass with Paget's disease.</p>
<p class="ql-align-justify">Fibrofatty tissue measuring 4 x 3 x 2.2 cm, partially covered by skin ellipse measuring 3 cm. Sectioning revealed a fairly defined solid, firm, creamy-colored mass measuring 2.8 x 2.2 x 2 cm. The mass is located 0.5 cm away from the deep margin and 0.2 cm away from the lateral margin.</p>
<p><strong><em><u>Lt. breast mass, excision:</u></em></strong></p><ul><li><strong>Invasive carcinoma of no special type, grade 2, with pagetoid spread to epidermis, with lymphovascular and perineural invasion, positive lateral margin, close deep margin (1 mm). </strong></li><li><strong>Stage pT2NxMx</strong></li></ul>
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