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<p class="ql-align-justify">Most of submitted fragments are blood clots and necrotic fragments with minimally reptesented tumor formed of irregular trabeculae of rounded cells with rather uniform </p><p class="ql-align-justify">rounded nuclei. The vast majority of cells show cytoplasmic vacuolations of variable size that appear to coalesce forming microcystic spaces.</p><p class="ql-align-justify">Picture is highly suggestive of chordoma, recommend for Confirmatory marker study (CK, S100, Brachyury)</p>
<p class="ql-align-justify">Predominantly cystic sacral tumor (highly suspicious for a cystic chordoma) that destroys the S1-S3 vertebrae, compresses the rectum and urinary bladder, and infiltrates the left piriformis and gluteal muscles, complicated by multiple enhancing intraspinal drop lesions at the D12 and L3-L5 levels, with no evidence of thoracic metastasis.</p>
<p class="ql-align-justify">Soft tissue fragments collectively measured 5.5x5x1.7 cm, totally embedded.</p>
<p><strong><em><u>Sacral mass, incision biopsy:</u></em></strong></p><ul><li><strong>Dominantly hemorrhagic material with few atypical round cells, suggestive but inconclusive of chordoma. </strong></li><li><strong>Recommended for confirmatory marker study. </strong></li></ul>
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