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<p class="ql-align-justify">Gastric mucosal fragments show background chronic active gastritis with identifiable Helicobacter pylori organisms, associated intestinal metaplasia, and architectural and cytologic changes consistent with focal high-grade dysplasia.</p><p class="ql-align-justify">Additionally, three fragments are ulcerated with related atypical round cell infiltrate with nuclear enlargement and hyperchromasia. To definitively characterize this atypical infiltrate, confirm or rule out malignancy, and establish its exact cellular lineage (e.g., epithelial or lymphoid), an immunohistochemical panel; <strong>CK, CD20, CD3, CD43, KI-67 </strong>is recommended.</p>
<p class="ql-align-justify">Chronic peripyloric and pyloric ulceration with moderate stenosis of the pylorus.</p>
<p class="ql-align-justify">Soft tissue fragments collectively measured 1 cm, totally embedded.</p>
<p><strong><em><u>Stomach, endoscopic biopsy: </u></em></strong></p><ul><li><strong>Atypical round cell infiltrate suspicious of malignancy.</strong></li><li><strong>Recommended for typing by immunohistochemistry.</strong></li></ul>
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