Gastric mucosa showing mild atrophy of glands and mild infiltration by lymphocytes and plasma cells. There is evidence of inflammatory activity manifested by some neutrophils infiltrating glands. H. pylori characteristic forms are seen. No evidence of intestinal metaplasia, atypia or malignancy.
Duodenal mucosa showing almost diffuse villous atrophy as the intestinal villi are significantly shrunken or partially flattened (moderate atrophy). The crypts (glands at the base of the villi) become deeper as the body tries to compensate for lost villi. There is a pathological increase in these lymphocytes within the epithelial lining with follicles. No evidence of specific granulomas. No evidence of atypia or malignancy.
Atrophic mucosa with a mosaic pattern and mild erythema in the stomach antrum, alongside an incompetent cardia and a duodenum characterized by atrophic folds, flattened villi, scalloping, and fissuring.
1- Gastric: soft tissue fragments collectively measured 1 cm, totally embedded.
2- Duodenal: soft tissue fragments collectively measured 1 cm, totally embedded.
Duodenum, endoscopic biopsy: