1- Lymph node shows preserved normal nodal pattern and hyperplasia of the lymphoid follicles which retain active and intact germinal centers with tingible body macrophages. Sinuses are expanded by numerous benign histiocytes with abundant coarse black anthracotic pigment-laden macrophages consistent with sinus histiocytosis and anthracosis.There is associated inflammatory cell infiltrate in subcapsular areas of lymph node with extension into perinodal fibrofatty tissue. No evidence of specific granulomas.No evidence of malignancy.
2- An encapsulated tumor with an organoid pattern of nests of rounded large epithelioid-like cells with abundant granular or clear cytoplasm. Cell borders are ill-defined.The nests are separated by a network of fibrovascular trabeculae. Some cells show enlarged nuclei, but there is no evidence of mitotic activity.The tumor capsule appears attenuated in many foci,with evidence of invasion by tumor cell nests.
Right-sided neck mass, CT Angiography: a well-defined, avidly enhancing lesion at the bifurcation of the right carotid artery that splays and encases the internal and external carotid vessels.
Two specimens were received:
Specimen 1 consisted of one nodule measuring 1.2 x 0.8 x 0.7 cm, grey in color, and totally submitted.
Specimen 2 consisted of two soft tissue pieces, the first measuring 2 x 1.5 x 1 cm with a grey cut surface, and the second measuring 1.5 x 1 x 0.8 cm with a brown color, totally embedded.
Rt. Sided neck mass, excision biopsy:
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