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<p class="ql-align-justify">Sections of the small bowel show a dense, transmural chronic inflammatory infiltrate composed of a polymorphic population of mature lymphocytes, plasma cells, and histiocytes interspersed with prominent fibroblastic proliferation, with relatively preserved tissue architecture.</p><p class="ql-align-justify"><br></p><p class="ql-align-justify">Immunostaining was done with appropriate positive and negative controls and revealed a polyclonal distribution of inflammatory cells, with CD20 highlighting reactive B-cell follicles and CD3 marking a population of interspersed T-cells; CD43 shows normal T-cell positivity with no evidence of aberrant co-expression in B-cells, while CK staining is restricted to the intestinal mucosal epithelium.</p>
<p class="ql-align-justify">Referred blocks for immunostaining of annular strictures causing small bowel obstruction.</p>
<p>Four referred paraffin blocks.</p>
<p><strong><em><u>Immunostaining of Small bowel, resection: </u></em></strong></p><ul><li class="ql-align-justify"><strong>Dense transmural chronic polymorphic inflammatory infiltrate with associated fibroblastic proliferation. </strong></li><li class="ql-align-justify"><strong>Immunohistochemical studies show a polyclonal lymphoid population with no immunophenotypic evidence of lymphoproliferative neoplasia.</strong></li></ul>
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