Partially ulcerated gastric mucosal fragments infiltrated by an invasive moderately differentiated adenocarcinoma. The tumor is composed of crowded, irregular, and angulated and cribriform glands exhibiting fused and back-to-back architecture with minimal intervening stroma. These neoplastic structures are set within a desmoplastic background and are lined by atypical epithelial cells demonstrating nuclear enlargement, hyperchromasia, pleomorphism, loss of polarity, and prominent nucleoli.
Follow up for large polypoidal lesion.
Soft tissue fragments collectively measured 1 cm, totally embedded in one cassette.
Gastric polypoidal lesion, endoscopic biopsy: