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<p class="ql-align-justify">Submitted brain glial tissue shows dense infiltration by neutrophils, lymphocytes, plasma cells and macrophages with related capillary proliferation and cell debris. No evidence of granulomas or tumors in this material.</p>
<p class="ql-align-justify">History of a brain abscess excised 9 years ago, presenting with a 5-day history of headache, whose current brain MRI reveals a large conglomerate of ring-enhancing lesions in the right temporo-parieto-frontal cortex causing significant mass effect, a midline shift to the left, and right uncal herniation—highly suspicious for recurrent or new cerebral abscesses—alongside stable left parieto-occipital encephalomalacia and a left-sided VP shunt.</p>
<p class="ql-align-justify">Soft tissue fragments measuring in aggregate 4.5 x 3.8 x 1.3 cm; the largest measures 1.8 x 1.5 x 1.3 cm, totally embedded.</p>
<p><strong><em><u>Right temporo-parieto-frontal cortex lesion, biopsy:</u></em></strong></p><ul><li><strong>Dense suppurative inflammatory reaction consistent with brain abscess.</strong></li><li><strong>Negative for malignancy.</strong></li></ul>
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