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<p><strong>SPECIMEN</strong></p><ul><li>Procedure: Radical cholecystectomy with liver resection.</li></ul><p><strong>TUMOR</strong></p><ul><li>Tumor Site: Gallbladder, not otherwise specified.</li><li>Histologic Type: Adenocarcinoma, conventional.</li><li>Histologic Grade: G2, moderately differentiated.</li></ul><p><strong>Tumor Size:</strong> Greatest dimension: 2.5 cm.</p><ul><li>Tumor Extension: Tumor directly invades adjacent liver parenchyma.</li></ul><p><strong>MARGINS</strong></p><ul><li>Margin Status: All margins are uninvolved by carcinoma and high-grade dysplasia.</li><li>Liver Parenchymal Margin: Uninvolved by invasive carcinoma.</li><li>Cystic Duct Margin: Uninvolved by invasive carcinoma.</li></ul><p><br></p><p><strong>Lymphovascular Invasion: </strong>Not identified</p><p><br></p><p><strong>Perineural Invasion:</strong> Not identified.</p><p><strong>Regional Lymph Nodes: </strong>pNX (regional lymph nodes cannot be assessed/not submitted).</p><p><br></p><p>Additional Pathologic Findings: Cholelithiasis.</p><p><br></p><p>PATHOLOGIC STAGE CLASSIFICATION (AJCC 8th Edition)</p><ul><li>Primary Tumor (pT): pT3 (tumor invades the serosa [visceral peritoneum] and/or directly invades the liver and/or one other adjacent organ or structure).</li><li>Regional Lymph Nodes (pN): pNX (regional lymph nodes cannot be assessed).</li></ul><p><br></p><p><br></p><p><br></p><p><br></p><p><br></p>
<p>Gall bladder mass.</p>
<p class="ql-align-justify">Received was a gallbladder specimen that measured 4 x 2 cm, accompanied by an attached segment of liver tissue that measured 5.5 x 3 x 2.8 cm. Examination of the gallbladder revealed a ruptured area suspicious for a mass, which measured 2.5 x 2 cm. Upon opening, the mucosal surface appeared ulcerated. The lumen contained multiple yellow calculi, with the largest stone measuring 1 cm in maximum dimension.</p>
<p><strong><em><u>Gallbladder and attached liver tissue, radical cholecystectomy:</u></em></strong></p><ul><li><strong>Adenocarcinoma, grade 2. </strong></li><li><strong>Tumor directly extends into the adjacent liver parenchyma.</strong></li><li><strong>All submitted surgical margins are negative for invasive carcinoma.</strong></li><li><strong>Cholelithiasis.</strong></li></ul>
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