Lymph nodes exhibits partial architectural effacement. The nodal parenchyma and adjacent fibroadipose tissues are significantly distorted by an organizing chronic sinus tract wall, characterized by dense collagenous stroma, active fibroblastic proliferation, and a rich network of newly formed capillaries. The inflammatory process is polymorphic and dense with an abundant population of mature plasma cells, histiocytes and small lymphocytes. Interspersed throughout are focal aggregates of polymorphonuclear neutrophils forming microabcsesses. Extensive deposits of coarse, brown granular hemosiderin pigment are noted both extracellularly and within macrophages, indicating chronic localized hemorrhage. Distinct caseating necrosis or well-formed Langhans giant cells are not identified. No evidence of specific granulomas. No evidence of atypia or malignancy.
4-month history of purulent discharge from the right inguinal area, found on examination to have an inguinal sinus tract communicating with a purulent collection in the femoral triangle, right inguinal lymph node excision to rule out tuberculosis or other chronic infectious etiologies.
Lymph nodes measured 1.6x1.3x0.8 cm, totally embedded.
Right Inguinal Lymph Node and Sinus Tract, Excision: