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<p class="ql-align-justify">Submitted material dominantly shows intact hyperplastic esophageal squamous epithelium with focal ulceration and related dense inflammatory cell infiltrate rich in neutrophils, lymphocytes, plasma cells with many cell debris. The residual non-ulcerated area shows moderate reparative dysplasia. No evidence of glandular metaplasia. Picture is consistent with severe GERD. No evidence of malignancy. </p>
<p class="ql-align-justify">Diffuse esophageal nodularity down from pharynx to the gastroesophageal junction.</p>
<p class="ql-align-justify">Soft tissue fragments collectively measured 0.6 cm, totally embedded</p>
<p><strong><em><u>Esophagus, endoscopic biopsy:</u></em></strong></p><ul><li class="ql-align-justify"><strong>Active inflammatory ulceration with moderate reparative dysplasia, consistent with GERD. </strong></li><li class="ql-align-justify"><strong>Negative for malignancy. </strong></li></ul><p class="ql-align-justify"><br></p><p class="ql-align-justify"><strong><u>Comment:</u></strong></p><ul><li class="ql-align-justify">Follow up endoscopy after treatment of active inflammation is recommended to ensure reversal of the observed dysplastic changes and to exclude the possibility of more serious pathology</li></ul>
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