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<p>SPECIMEN</p><ul><li>Procedure: Radical abdominal hysterectomy</li><li>Specimen Integrity: Submitted in two parts (uterus with adnexa, separate soft tissue piece, and external iliac lymph nodes).</li></ul><p>TUMOR</p><ul><li>Tumor Site: Cervix (with extension to the vagina).</li><li>Histologic Type: Carcinosarcoma (Malignant Mixed Müllerian Tumor / MMMT).</li><li>Tumor Size: 4.3 × 4.5 × 3.5 cm (greatest dimension: 4.5 cm).</li><li>Macroscopic Appearance: Solid, firm, gray-colored mass almost entirely replacing the cervix (Barrel shaped) .</li></ul><p>Tumor Extension:</p><ul><li>Uterine Corpus / Corpus Extension: Not identified</li><li>Vaginal Extension: Present (extends to the vagina).</li></ul><p>Perineural Invasion: Not identified.</p><p>Lymphovascular Invasion (LVI): Not identified.</p><p>MARGINS</p><ul><li>Parametrial Margin: Negative for carcinosarcoma.</li><li>Distance of tumor from margin: Less than 0.1 mm (close margin).</li><li>Vaginal Margin: Negative for carcinosarcoma.</li><li>Distance of tumor from margin: 0.5 cm.</li></ul><p>ADJACENT ORGANS / TISSUES</p><ul><li>Endometrium: Uninvolved (0.3 cm thickness).</li><li>Myometrium: Uninvolved (1.5 cm thickness).</li><li>Right Ovary and Fallopian Tube: Negative for tumor; unremarkable.</li><li>Left Ovary and Fallopian Tube: Negative for tumor; unremarkable.</li><li>Separate Soft Tissue Piece: positive for the same tumor.</li></ul><p>LYMPH NODES</p><ul><li>Regional Lymph Nodes: external iliac lymph nodes examined.</li><li>Total number of lymph nodes recovered: 4.</li><li>Number of positive lymph nodes: 0.</li></ul><p>PATHOLOGIC STAGING (AJCC 9th Edition / FIGO 2018)</p><ul><li>Primary Tumor (pT): pT2a1</li><li>Regional Lymph Nodes (pN): pN0 (No regional lymph node metastasis).</li></ul><p>FIGO Stage: Stage IIA1.</p>
<p>Uterine cervical mass.</p>
<p class="ql-align-justify">Radical hysterectomy received into two containers:</p><p class="ql-align-justify">1- Panhysterectomy: The Uterus measured 8.5 x 4.5 x 3 cm with an endometrium measuring 0.3 cm in thickness and a 1.5 cm thick uterine Wall. Sectioning revealed barrel shaped cervix measured 3.8 cm in length, almost entirely replaced by a solid, firm, gray-colored Mass measuring 4.3 x 4.5 x 3.5 cm. The Right and Left Ovaries measured 1.7 x 1 x 0.7 cm, each. Right and Left Fallopian Tubes measures 3.5 x 0.5 cm, each.</p><p class="ql-align-justify">Received separately was one soft tissue piece measuring 4 x 3 x 1 cm, which showed a bloody colored and spongy cut surface.</p><p class="ql-align-justify"><br></p><p class="ql-align-justify">2- External iliac lymph nodes: fibrofatty tissue measured 2x1.5x1 cm, entangling four lymph nodes, largest measured 1 cm.</p>
<p><strong><em><u>Uterine cervix mass, Radical hysterectomy:</u></em></strong></p><ul><li class="ql-align-justify"><strong>Carcinosarcoma (Malignant Mixed Müllerian Tumor) of the cervix, measuring 4.5 cm in greatest dimension, with extension to the upper vagina.</strong></li><li class="ql-align-justify"><strong>Parametrial and vaginal resection margins negative for malignancy (parametrial margin close <0.1 mm; vaginal margin 0.5 cm).</strong></li><li class="ql-align-justify"><strong>No lymphovascular or perineural invasion identified.</strong></li><li class="ql-align-justify"><strong>Four (4) regional pelvic lymph nodes negative for metastasis (0/4).</strong></li><li class="ql-align-justify"><strong>Endometrium, myometrium, and bilateral adnexa are negative for tumor infiltrtaion.</strong></li></ul>
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