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<p class="ql-align-justify">Mural cellular tumor composed of fascicles or whorly bundles of proliferating spindle cells with fusiform or blunt ended (cigar-shaped) elongated nuclei. There is focal palisading of nuclei. Anaplasia is moderate and mitosis is increased (about 7-8/50 HPF). Margins of excision included are positive for tumor infiltration. </p><p class="ql-align-justify">Picture is consistent with high risk gastrointestinal stromal tumor (GIST). Marker study (CD117, CD34, actin, DOG1, S100, Ki-67) is recommended to confirm tumor type and to exclude other possibilities of stromal tumors, mainly leiomyosarcoma and malignant peripheral nerve sheath tumor. </p>
<p class="ql-align-justify">Gastric mass, suspected gastrointestinal stromal tumor.</p>
<p class="ql-align-justify">Mucosal fragment measured 5x3x2.7 cm, showing solid firm greyish white mass measuring 4.8x3x2.5 cm. No evidence of surrounding tissue clearance. </p>
<p><strong><em><u>Gastric mass, laparoscopic resection:</u></em></strong></p><ul><li class="ql-align-justify"><strong>Consistent with gastrointestinal stromal tumor (GIST), high risk.</strong></li><li class="ql-align-justify"><strong>Recommended for confirmatory marker study. </strong></li></ul>
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