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<p class="ql-align-justify">Fragmented biopsy showing tumor composed of tubular and few papillae with delicate fibrovascular cores, covered by pseudostratified columnar epithelium. Few of these columnar cells show cytoplasmic vacuoles and some cells show enlarged hyperchromatic nuclei (mild atypia). Picture is consistent with ampullary adenoma, intestinal type with mild atypia. </p>
<p class="ql-align-justify">Obstructive jaundice. Retroampullary biopsy was taken.</p>
<p class="ql-align-justify">Soft tissue fragments collectively measured 0.7x0.6 cm, totally embedded.</p>
<p><strong><em><u>Ampulla of Vater, Endoscopic biopsy:</u></em></strong></p><ul><li><strong>Consistent with ampullary adenoma, intestinal type with low grade dysplasia. </strong></li><li><strong>Recommended for follow up.</strong></li></ul><p><br></p><h5><strong><u>COMMENT:</u></strong></h5><h5>Duodenal lesion could be precancerous and complete mucosal resection of the lesion is advised, first to confirm the diagnosis and to exclude the possibility of any concomitant un-sampled invasive growth and second to minimize the risk of progression.</h5><p><br></p>
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