Two of submitted fragments show atypical round cell infiltrate, showing hyperchromatic nuclei and abundant eosinophilic cytoplasm, others having eccentric nuclei and eosinophilic cytoplasm. These cells are seen related to extensive surface ulceration. Rest of fragments show moderate atrophy of glands and moderate infiltration by lymphocytes and plasma cells. Some neutrophils are seen infiltrating glands thus indicating activity. H. pylori characteristic forms are seen colonizing glands. These cells could be histiocytes, epithelial, or lymphoid. Marker study (CD68, CK, LCA and CD20) is recommended for definitive typing.
Gastric giant ulcers at fundus extending to the body.
Soft tissue fragments collectively measured 1 cm
Stomach, endoscopic biopsy: