Sections show a dermal non-capsulated nodular lesion composed of proliferating spindle fibroblastic cells entrapping tiny spaces full of RBCs, but no definite endothelial lining. Anaplasia is mild and mitotic activity is increased. Margins of excision are free of tumor, however, deep margin is close (0.1 cm). Picture is consistent with Kaposi sarcoma. Marker study (HHV8, CD34, ERG, HMB45, CK) is recommended for confirmation.
Foot ulcerative lesion.
Skin ellipse 1.7x1.5x0.7 cm, showing fairly defined ulcerative mass measured 1.4x1.3 cm. Margins of excision ranged from 0.1 to 0.2 cm. The specimen was totally embedded.
Foot ulcer, Excision: