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<p class="ql-align-justify">Ulcerated rectal mucosal fragments infiltrated by sheets of crushed atypical medium to large -sized cells. The neoplastic cells exhibit high nuclear-to-cytoplasmic ratios, scant cytoplasm, and hyperchromatic nuclei. Frequent mitotic figures and apoptotic bodies are identified. The background stroma shows desmoplasia and foci of necrosis.</p><p class="ql-align-justify">Picture is that of malignant undifferentiated large round cell tumor, recommended for typing by marker study (CD20, CD3, CK, Synaptophysin, HMB45, CD43, Ki-67).</p>
<p>Rectal mass</p>
<p class="ql-align-justify">Soft tissue fragments collectively measured 1.2 cm, totally embedded.</p>
<p><strong><em><u>Rectal mass, endoscopic biopsy :</u></em></strong></p><ul><li><strong>Malignant undifferentiated large round cell tumor. </strong></li><li><strong>Recommend for typing by marker study. </strong></li></ul>
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