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<p class="ql-align-justify">Smear shows many papillary and clusters of malignant epithelial looking cells with hyperchromatic nuclei exhibiting moderate anaplasia. Some cells shows intracytoplasmic vacuoles. Background shows a moderate number of mature small lymphocytes and neutrophils with reactive mesothelial cells. According to The International System for Reporting Serous Fluid Cytology (ISRSFC); this is Category V. </p>
<p>Ascitis</p>
<p class="ql-align-justify">One smear was prepared and stained from submitted 10 ml yellowish fluid.</p>
<p><strong><em><u>Ascitic fluid, cytology</u></em></strong>:</p><ul><li><strong>Positive for malignant clusters, consistent with metastatic adenocarcinoma.</strong></li><li><strong>(Category V according to The International System for Reporting Serous Fluid Cytology, ISRSFC). </strong></li><li><strong>Recommended for confirmatory metastatic work up.</strong></li></ul><p><br></p><p><strong><u>COMMENT</u></strong><u>:</u></p><p>Such cytological features may be rarely produced by mesothelioma. Correlation with radiological findings (to ensure or exclude the presence of omental mass lesion) as well as careful metastatic work-up are both advised to establish a final diagnosis.</p><p><br></p><p><br></p><h5 class="ql-align-justify"><br></h5>
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