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<p class="ql-align-justify">Tissue fragments show medullary bone replaced by dense fibrous tissue and a marked chronic inflammatory infiltrate of mature lymphocytes, plasma cells and few neutrophils. The stroma contains coarse, dark brown-to-black granular pigment predominantly engulfed by sheets and clusters of histiocytes. No cytologic atypia or malignancy.</p>
<p>The patient had a non-union of the right femur with a broken intramedullary nail (IMN).</p><p class="ql-align-justify">The surgeon removed the distal part of the broken IMN and extracted tissue for a biopsy and histopathology.</p>
<p class="ql-align-justify">One soft tissue fragment measured 1x0.8x0.7 cm, totally embedded.</p>
<p><strong><em><u> Femur non union fracture, biopsy:</u></em></strong></p><ul><li><strong>Chronic non-specific inflammation with associated Fibrosis. </strong></li><li><strong>Negative for malignancy. </strong></li></ul>
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